Quetteville station was opened on July 7, 1862 by the Compagnie des chemins de fer de l'Ouest.
At the time, the company was opening up the 25km second section (between Pont-L'évêque and Honfleur) of its Lisieux-Honfleur line. On this section, in addition to the end stations, it is the only intermediate station.
The Pont-Audemer-Quetteville section was opened to traffic on June 8, 1889. From then on, the station became a branch station, and was extensively remodeled and enlarged.
A new passenger building, built a few hundred meters from the old one, now occupied the center of the 2 branches of the Y at the new junction.
The freight facilities remained in their original location, close to the original passenger building, which was reused as a simple dwelling.
Passenger traffic ceased in autumn 1969. From 1995 to 2005, the "Pontaurail" association operated a railcar (X2426) as a tourist service between Pont-Audemer and Honfleur.